ANTIDOTARIA; OR, A Collection of ANTIDOTES AGAINST THE PLAGUE, AND OTHER
Malignant Diseases.
TOGETHER, With some Decent and Useful
Remarks,
on the late
Pharmacopeia Londinensis,
in a Letter to the
President
and
College
of PHYSICIANS; shewing the Necessity of a farther Reformation of their new LONDON DISPENSATORY.
By
JOSEPH BROWNE,
L.L.M.D.
LONDON: Printed for
J. WILCOX,
at the
Green-Dragon
in
Little-Britain;
and sold by
J. ROBERTS,
in
Warwick-Lane. 1721.
TO The most Eminently Learned, the
President
and
Community
of the ROYAL COLLEGE of
PHYSICIANS,
LONDON.
Gentlemen,
T HE Intention of the following Pages, with Difference to your illustrious Body, is with all submission laid at your Feet, carrying no other Views along with it, than to promote, the further Knowledge of
medicine,
the exact and artful Composition of which is so highly Necessary, and conducive to the Welfare of Mankind, and the Utility of the Publick.
I REST assured of a candid Reception from the Nature of the Design, which I have the vanity to think you will favour, because it is only level'd at a Reformation some of the Errors in Composition that have crept into former, and are still retain'd in your last Edition of the
London Dispensatory,
and a further Recommendation of the many excellent Prescriptions, which you have with Justice to the
Profession,
continued and publish'd to the World, all which I shall endeavour to support by Authority, Reason and Experience; hence, I flatter myself with every thing that can be expected from a
Society
so distinguish'd for universal Literature, as well as their particular Knowledge in
Medicine.
THIS is a meer Trifle which I offer, only as an Essay to what I have ready for the Press, and to which I doubt not of your generous Approbation; for as 'the Study of your Lives is devoted to do Good, so you will certainly promote every Thing that tends to that great End; and what is of more Importance than to preserve Life, and restore to Man that valuable Blessing of Health?
THIS Collection of
Antidotes,
altho', no
Epidemical Disease
should happen (which God in his Mercy avert) is of universal Tendency, and speaks for itself: The Authors were all Physicians of great Experience, some of whom liv'd thro' five or six
Plagues,
in which they had been singularly successful; and after that devouring Flame was Extinguish'd, they had in all their succeeding Practice, still a mighty Esteem for such Antidotes and Alexipharmicks as had been Serviceable to them, when they stood so much in need of their Assistance, on which Occasion they invented and introduced a whole Set or Collection of 'em, into Practice among which you have the various Prescriptions of Sir
Walter Rawleigh's
great Cordial, that of Sir
Kenelm Digby's
Diaphoretick, Gascoyne Powder, with the Goa-Stone, and a great Variety of the
Lapis Contrayerva,
with many others; all which are very valuable in their Kinds, and consequently, I doubt not but the Publication of this will meet with a Reception equal to the Merits of those learned Gentlemen, who were the Compilers of the several Recipe's and Prescriptions therein contain'd, which were certainly Studied and found Useful for the publick Service.
NOW, let, me beg leave of your learned
Society
to make some decent and modest Remarks upon your last Edition, of your
Pharmacopeia
that from the Justness of those Observations, you yourselves may Judge of the Necessity there is for a Reformation of the same, and from the Specimens I shall give, make the World sensible of the Usefulness of such an Undertaking, which, with the last Regards due to your venerable Body, I submit to impartial Judgment. And in the first Place, I shall not wast Time, either upon the Method, or Materials you have made Choice of in the Simples conducive to your
Dispensatory,
whether Roots, Barks, Woods, Herbs, Flowers, Fruits, Seeds or the like, but do think it wou'd have been a Justice due to the Publick, as well as an Advantage to the
Profession
to have inform'd them, which of those Simples most constantly are in Use, which are seldom used, and which are never used at all; which Things are very Material, that Time and Money may not be thrown away upon what is perfectly Useless; as the Roots of Anthorae an Exotick, called the Counter-poison to Monkshood, not Traffick'd in, and of no Virtues that are recommended by the Experience of the Faculty. 2dly. Arundinis Saccharina; the common Reed and Sugar-Cane Roots of no Medicinal use. The Roots of Kings Spear or Asphodel, Male and Female, not Us'd or even Sold in the Druggist, or Apothecaries Shops, and many more.
THE next are those which, are seldom, or very rarely used, such as the
Hermodactyls,
Woad, Fullers Thistle, Hog-Fennel, Stinking Gladon, and an hundred others mention'd to little or no Purpose, which had been better left out, both for the ease of the Apothecary, and the Prescriber, who is at first embarrass'd in so large a Field of Materials, loaded by some Authors with great Encocomiums of the Feats they have done in Physick, which are too apt to flatter and disappoint the Presumptions of a young Practitioner.
I SHALL pass by the rest of the Simples in this short Account, and leave 'em to a stricter Enquiry, when I come to publish the
Pharmacopeia Reformata,
and so proceed to some more material Observations, among which, I shall first take Notice of, the Oxymel scilliticum, which you have Prescrib'd just in the same manner as formerly,
viz.
Three
Pounds of Clarified Honey, to two Pounds of Vinegar of Squills;
whereas in Justness to the Operation, and Effects of this
Medicine,
here should be three Pounds of Vinegar of
Squills,
to two Pounds of Honey, otherwise the
Medecine
is so clogg'd with the Honey, that the Efficacy thereof is lost, and the
Acetum
hath not power to assist the Digestion, cut the viscous Flegm, discharge Wind and sour Belchings from the Stomach, and strengthen the Appetite; for which it is a noble Remedy, was it not so very Nauseous; but it may be excellently adapted by a skillful and judicious Physician, who by mixing equal parts of the
Acetum scilliticum
and Oxymel will gain his Intentions.
I CANNOT be surpriz'd that you have overlook'd this among so many other Compositions, which are so Faulty, that they are not capable of being made up or if they could, wou'd be of no Use, since you are pleas'd to persist in your daily Practice to prescribe Galbanum along with Ammoniacum, in order to be dissolv'd, in black Cherry-water, or other the like Vehicle, and are angry with the Apothecary, when he tells you plain, that he knows not how to dissolve
Galbanum
in an aqueous Body, tho'
Ammoniacum
will familiarly do it; if this Point had been clear'd up in your last Edition, of the
London Dispensatory,
and new Rules given to the Apothecary, how to make his Dissolution of
Galbanum,
this wou'd have been a great Improvement, and given a New turn to the Dispensations of Medicines, but till then, we shall believe it was not so artfully Corrected, as we had Reason to expect from Persons so well qualify'd; otherwise the
Spiritus Lavendulae compositus
would hardly have remain'd in the Condition it stands, considering it is such a
Farrago
of inconsistences unskilfully blended, the Produce of which, is nothing at all; when at the same time the simple Spirit of Lavender, is so excellently useful, and may be enrich'd at the Physician's pleasure, with all the Volatile Aromaticks,
&c.
according to the Nature of the Case, becoming by this Means a
Spiritus Lavendulae Extemporaneo Compositus.
YOUR
Aqua Paeoniae Composita,
or Peony-water Compound, is an excellent Prescription, but wants much of what it was from
Langius,
who calls it his
Epileptick Water,
which Receipt I shall give you (as it was Originally) in the
Pharmacopeia Reformata;
in the interim it is high time to expunge
Gilbert's Water,
least some evil minded People shou'd deceive themselves, and others, in putting their Trust therein.
As to the Treacle of
Audromachus,
and
Mithridate,
of which I can find no Reformation made in your last Edition; it is one grand Medley of a multitude of Simples jumbl'd together without Order or Design; the greatest Part of which are either useless, or ineffectual. I shall satisfie my own Opinion only to declare that as generally us'd, and apply'd, they are both dangerous Medicines ill prepar'd, very Hot and of disagreeable Qualities to the Intentions they are administred. The grand Reason that has induc'd all Sorts of People to the Use of them, have been drawn from the Authority and Experience of the Antients;
Galen
says they, hath spoken in Praise of
Treacle
in two Pieces of his, directed to
Piso,
and
Pamphilianus.
To which I answer, that the Authority cited, is of no force, because they do not appear to be
Galen's
Writings, but falsly attributed to him, which is the more Evident from the Stile and Manner of Writing, which is foreign from that of
Galen's,
besides there are several Terms, and Words made Use of not elsewhere to be found in the said Author's Works, according to the learn'd
Mercurialis,
who says,
in eo plurima verba a Galeno nusquam usurpata, fabulosae aliqua & stylus totus pene diversus reperiuntur.
The same Author says, there ought not to be the least Fault in any of the Simples, that enter that Composition, speaking of
Treacle Vitium enim unius Medicamenti totum Compositionem evertit.
EVERY Body knows the great Abuse in the Choice of Vipers, and that of the
Malabathrum,
which not one in an hundred makes a right Use of; besides this, the
Myrrh
we use, setting aside the smell, is nothing like that describ'd by
Dioscorides,
but rather
Bdelliams,
whereas the Troglotick is the fame, and we have no
Opo-Balsamum,
true
Costus, Schaenanth, Dictamny
of
Crete,
or
Falernian Wine.
The generality of the
Opium
us'd at this Day, is nothing near so fine, or good as
Mathiolus
relates, and scarce seems to be like what
Dioscorides
describes: For it is a perfect
Meconium
at this Day, as may be evidently Proved,
THE
Mithridate
commonly met with in the Shops, is in the same Condition, having the same Faults and Imperfections, and therefore ought to be rejected, being too hot and acrid for the Intentions it is generally Prescrib'd, consequently it wants a considerable Reformation, or else ought to be expung'd the
Dispensatory.
THE Confection of
Alkermes,
altho' very prudently divested of its Perfumes now a-days, is a Composition very unartfully Invented and Describ'd by the
Arabians,
and very little Reform'd and Amended by the Moderns, who still closely pursue the Errors of the
Arabian Physicians:
Indeed the
Lapis Laruli
has been long since thrown out, and there remains little behind in this Medicine, which bears a high Name, but what we may expect from the Juice or Syrup of the
Chermes-Berry
with better Success; for as to the
Aloes Wood,
we know little or nothing of it, and the Leaf-Gold therein, is a meer Amusement to Deceive the Credulous.
Rondeletius
instead of speaking in its Praise gives a severe Caution against the Use of it, which is Back'd by Mr.
Ferrier,
a Physician of
Tholouse,
who blames Physicians for the too plentiful Prescribing thereof: See the
Annotations
and
Observations
of Mr.
Guillemeau.
The Confect of
Hyacinth
bears a great Resemblance to this, only that the last seems to be endowed with no Cordial Virtue at all: Notwithanding the great Boasts made of it, from the Fragments of Precious-Stones, that enter the Composition, by the splendid shew of which, together, with the Leaf-Gold, many are induced to believe it is capable of performing Wonders.
AS I was treating of
Mithridate,
I must take the Liberty to return to the Subject, to shew that when
Pompey
found the Receipt thereof written in
Mithridates
own Hand, after the Defeat of that Prince, which he esteem'd as a vaulable Secret; it was Compounded but of very few Simples, and those very common ones according to the following
Distick.
Antidotus vero multis Mithridatica fertur
Consociata Modis, sed magnus scrinia Regis
Cum rapperet Victor, vilem deprendit in illis
Synthesim, & vulgatâ satis Medicamina risit:
Bis denum rutae folium, salis & brevegranum
Juglandás
que
duas, totidem cum corpore ficus:
Naecortente die pauco conspersa Lyaeo
Sumebat metuens, dederat
que
pocula tutor.
THIS Composition then consisted, only of two Walnuts, two Figs, Twenty leaves of
Rue
stamp'd together, with a little Salt; and this was reckon'd a sovereign Antidote against any maglignant Air for 24 Hours together, it being sufficient for three or four Morning Doses, drinking after it a Glass of white Wine
THE next thing to be enquir'd into, is to know the Reason, why you still admit Leaf-Gold into several Preparations, since you very well know it is neither Cordial, Corroborative, Alterative, or does it any wise contribute to the Nutrition of the Parts according to
Galen,
in his Commentary on the first Book of
Hippocrates, de ratione Victus in Acutis.
It can by no Means be call'd an Alterative, in that the natural Disposition of the Body cannot be affected by Reason of the Solidity of its Parts, so that it can neither heat or cool, dry or moisten the solid, or fluid Parts, and how it becomes Purgative I cannot imagine; all which makes good what
Julius Caesar Scaliger,
says in his Exercitations against
Cardan
Exerc. 272. There ought to be some Resemblance, some likeness in Configuration of Parts; between what gives the Nutriment, and the Body that receives it. Metals are proper to unite with, and feed Metals, but are imcompatible, and foreign to the subsistence and increase of Animals. If Gold is good in any Disease, it must certainly be so in the
Hypochondriack, Melancholy,
especially when it is administred, not as the
Arabians,
in Pills or Powders, or as the Chymists in Potions like their
Aurum Potabile,
but plentifully in Specie, or Golden Showers; nay, if the Physician cou'd but prescribe
Bank
Bills, his prescriptions would infallibly Cure all the Vapours in Town. This is a Specifick, even against
South-Sea
Head-Ach, which, is otherwise an incurable Disease.
AND here I cannot forbear to hint at the present use of
Ivory,
that is still continued, and recommended in many good Medicines, when every Body knows, and is thoroughly perswaded that
Harts-Horn,
has an hundred times the Virtue, since the other neither discovers Smell or Taste, or any Quality to recommend it for an efficacious Medicine; several Physicians have long since exploded it, as
Durel Hantin, Mercurialis, Baccius, Sylvaticus Erastus, Albertus, Sebizius,
and others; but
Ambrose Parey,
by dint of Reason and Experience refutes, all the pretended and imaginary Qualities assign'd to this useless and insignificant Drug.
THEREFORE it becomes more my Admiration, that Gentlemen who have consulted, and weigh'd all these things together in the Balance of Reason, should still continue the Use of many useless, and extravagant Drugs, which are now directed in the several Compositions of your
Dispensatory,
many of which are rarely, or not to be got at all, and others at a very dear Rate, and good for little or nothing; the first of which I mean is, the Bone of a Stags Heart, the others are Ambergreese, Musk, and Bezoar so frequently prescribed on all Occasions, in the last of which there are so many vile Cheats practic'd, that it is a pity it should lye in the power of avaritious, and designing Men to Cozen and Deceive the World, with such vile Frauds.
TWO Parts in three of the Bezoar, of which is sold and made Use of in the Shops is, Factitious, and the other that is Natural, is only fit to Deceive such as are willing to be Deceiv'd, and take a Pleasure to be carry'd down with the Stream of popular Errors. As to the Factitious, it is generally made up of
Gall-Stones,
found in the Gall-Bladders of Oxen,
&c.
and
Lemnian Earth
findly ground with a little
Ambergreese,
and so form'd into Stones of various Sizes and Figures; and thus the subtle Artist cheats the Apothecary with his Counterfeit Stone, and the Physician comes into the Confederacy, by prescribing his Bezoartick Bolus, or Powder to pick the Patient's Pocket: This fallacy upon the credulous Sick, will in a little time become as despicable, as the vain Pretentions of the
Alchymists,
with their
Aurum Potatabile,
their
Sulphur
of
Metals,
and
Powder
of
Projection,
with which they Bubble the Ignorant, and blind the Eyes of the more discerning part of Mankind.
I HOPE to God, that you Gentlemen, who have both Honour, Justice and Judgment, will put a stop to these Deceits whereby the People are Cheated with false Medicines, which under the pompous Pretensions of curing more Effectually, are made a Handle of, to extract Gold and Silver from the Patients Purse: A Reformation of these things would be a great Advantage to all Parties, and who can we expect it from, but your learned Body, who by your Example, and Authority have Power to Reform, and at the same time inform the World what your Opinions are in relation to such costly Drugs, as
Bezoar,
and whether the good Effects and Virtues thereof are answerable to the Physicians Expectation, and that of the Patient; if not, that you wou'd ingeniously declare this Stone naturally, as brought from
India,
and unsophistieated hath no more Virtue than some of our Foreign Earths, or Domestick Chalks.
IT is pretended by the Advocates for this Stone, that it is a most noble
Alexipharmick,
and is both
Cordial
and
Sudorifick,
tho' it does not appear from the Composition of its Parts, being Gross and Earthy, how it can encrease or otherwise alter the Motion of the Blood, or exhilerate the Spirits, which it seems not to have power to fortifie, and support. If this be so then, let us submit to the force of Truth, which we find publish'd in the Writings of some of the best Physicians of
Europe,
which Mr.
Guybert
hath accurately quoted; let us submit Opinion, I say to Truth, which is one and the same throughout the World.
Nic Boccangelinus
Physician to the Empress, and a very knowing
Spaniard,
in a Treatise of
Malignant
and
Pestilential Fevers.
Chap. 17. Condemn's the Use of
Bezoar,
thus; some make up Cordial Powders with
Bezoar, Pearl, Coral,
&c. which strangely Deceive them, for, all these things encrease the Obstructions, which encourage the Fever, the Materials being gross, earthy, and Unactive, foul the Stomach, clog the
Lacterals,
and stop the
Mesaraick
Vessels, so that the Blood which is Contaminated with the malignant Vapours, hath not power hereby to refine itself.
Hieron: Ruleus,
a learned Physician of
Ravenna,
in his Commentaries on the 7th Chap. of the 3d Book of
Celsus
exposes the Cheat after this manner; I own, says he, having often prescrib'd the
Bezoar Stone,
in Malignant, and other Fevers to several Persons of Quality, from 8 to 16 Grains, I never could observe any good Effect from it, by any sensible Operation, or Amendment in the Patient; but this we commonly Prescribe to the Rich and Great, by way of Complement, it being very dear: Besides let me Caution you, says he, for there are a great many Counterfeit, or false Stones, which I found by Experience in the last Sickness of Pope
Clement
the 8th, so that out of forty, which were brought me, I cou'd scarce meet with one good one.
MARTIANUS
a
Roman
Physician in his Commentaries upon
Hippocrates,
says, that the
Bezoar Stone
is nothing else, but a meer Name and Opinion without any Virtue, which he knows to be true upon repeated Tryals;
Rodericus a Fonseca,
a celebrated Professor at
Padua,
in a Tract of his on
Malignant Fevers,
ingenuously owns, that he never saw any laudable Effect from it, tho' he had frequently us'd it:
Johannes Colle
a learned
Italian,
and Physician to the D. of
Urbino,
in a Book of his call'd
Cosmitor Medicans,
or a large Treatise of the
Bezoar Stone,
makes severe Remarks on those, who boast of the Virtues of
Bezoar,
without any Reason, and on those who use it in all Diseases, like a Stall for all Horses.
Theodorus Angelutius
speaking of the Cure of
Malignant Fevers,
condemns it in these Words; I advise all Physicians, says he, against the use of this Stone, since it is a Drug that is good for nothing at the best; and all Men of sincerity, who are most worthy of Credit confess it, and I myself solemnly protest, that I never cou'd find the Sick relieved thereby, how easie it is, then for every one to Judge of the Danger there is in Confiding in so uncertain and frivolous a Medicine, when the Patient labours under a
Malignant Fever,
instead of a better approved, and more successful Remedy.
Thomas Minadous,
in his Book of
Fevers,
says thus; I cannot so much, as admit, or have ever met with any occult Quality in this
Bezoar Stone,
by which means it could prove serviceable in any Kind of
Fevers;
and therefore believe they are all fabulous Accounts, and old Womens Tales, that have been told either by the
Arabians,
or the Moderns; for I have try'd it several Times in several Diseases, without finding any Relief or Advantage from it.
Aloisius Mundella,
in his Experiments on
simple Medicines,
confirms what all the rest have said, whom I have quoted before.
PERMIT me, most excellent and learned Collegues, to say a Word or two about the Drug
Sena,
which enters so many of your well chosen Compositions, and which I have the Vanity to think you have not all met with in the common Treatises of
simple Medicines,
tho' the Subject fell in my way, when I consulted all the Authors I could then come at in compiling my
History
of
Drugs,
from
Pomet, Lemery Tournefort,
&c. The
Sena,
which
Mesue
from the
Persians,
calls
Abalzemer,
is a Plant or Shrub, the Leaves whereof Resemble those of Liquorice, it shoots up and spreads with many small Branches, which are very pliant, the Flowers are yellow, with certain Threads or red Streaks underneath, after which shoot forth certain Follicula or Buds closely folded, which hang upon the Plant, by a slender Tail, which is very fine, and naturally flat; these Buds when Ripe easily fall by the force of the Wind, and contain in them a Seed which is of a greenish black Colour, and so like the Stone of a Raisin, that it is hard to know the difference;
Serapion
in his Book of
Simples
says, these Buds are longish, and in form of a Cross, in which the Seed is lodg'd. They are much Deceived, who think that the Tree which
Theophrastus
calls
Colutea
to be our
Sena;
because the
Colutea
which the
French
call
Baguenaudier
bears large
Follicules
or
Buds,
which the Shepherds and Pesants gather to feed their Cattle with, besides, there is a vast difference, in that the
Sena
is an Herb or Plant that lasts but a few Months, and the
Bagnenaudier
is a Tree that continues many Years; notwithstanding which the same Virtues have been ascribed to the last, as to that of
Sena,
and the Merchant impos'd upon as well as the Druggist in buying the one for the other.
Mesue
says, that the
Sena
hath much more Virtue and Efficacy in the Bud than the Leaf, especially if of the Dark green Colour a little bitterish, stiptick and astringent in Tast, and gather'd when fresh, for otherwise the Virtue is lost. The white Buds are good for nothing, the green Leaves, better than the white, and the thick ones than the thin, but the Stalks of no Use at all; and this agrees very well with what
Matthiolus
writes in his learned Commentaries on
Dioscorides,
he says indeed, there are two Sorts of these Buds, the one of which is gather'd when dry and fallen from the Plant, which have no Virtue in them, and the other is gathered upon the Plant before it is dry and wither'd, and these are thick Leaves, and full of Sap, being afterwards skillfully dry'd in the Shade.
Manardus,
a Physician of
Ferrara
maintains, that the Leaves of the
Sena
have a greater Purgative Quality than the Buds, but then he takes 'em for such as dropt from the Tree ready dry'd; but
Fernelius
who was undoubtedly a more knowing Judge of Medicine, follows
Mesue
and
Matthiolus
in preferring the
Buds
to the
Leaves,
and
Sylvius
subscribes to the same Opinion, in his Commentaries upon
Mesue,
Whoever hath a Mind to Use the Buds, must observe this Description, but such as like the Leaves better, must chuse those of the brightest Colour, large and fresh, and free from all Smell, rejecting the pale and dead Colour'd as useless. Our Druggists are often very negligent in mixing all together, without Choice or Distinction. With submission to the more learned, I think we generally under Dose this Medicine in our Compositions, and Preseriptions.
Serapion
orders from a Dram, to two Drams in Powder, and half an Ounce to five Drams in Decoction,
Actuarius
only one Dram, and in Decoction half an Ounce;
Fernelius
directs two Drams in Powder, and six in Decoction, but half an Ounce in the Infusion. Your
London Dispensatory
prescribes only a Scruple of
Sena
in Powder, and half a Scruple of
Rhubarb
and
Polypody
in seven Drams of
Electuarium Catholicum,
and two Drams only in the Decoction of
Gereon,
and in the
Lenitive Electuary,
to one Ounce a Dram of
Sena,
with a Scruple of that and
Polypody
in Decoction, in the larger compound Powder of
Sena,
half a Dram, and in the less 24 Grains. The Magisterial Syrup of Apples hath a Dram of
Sena
to an Ounce, but the Purging Syrup only a Scruple infus'd to six Drams. Syrup of Roses with
Sena
hath indeed a Dram to six Drams of the Syrup. I shall conclude this Head, with the form of a Purging Potion of
Sena,
from an eminent Physician of our own, who Practiced upwards of sixty Years.
TAKE of fine
Sena,
cut small six Drams,
Salt
of
Tartar
two Drams, Juice of
Lemons
one Ounce, white Wine four Ounces, infuse six or seven Hours, in a Glass Vessel, then strain, and infuse therein all Night
Electuary
of
Carthamum
three Drams, the Juice of Apples one Ounce: In the Morning clarifie this with the white of an Egg, and to the strain'd Liquor, add Syrup of
Roses,
with
Agarick
six Drams,
Cinamon-Water
two Drams, the zest of half an Orange Peel. Notwithstanding the large Quantity of
Sena;
this is a Medicine of a nice and delicate Operation, without giving Gripes or Colick, and yet moves Ten or Twelve times.
IN order to introduce our
Antidotaria,
it may not be amiss to give a Specimen of the Reformation of two grand Prescriptions, which I have already hinted at to be faulty, in the
Pharmacopeia Londinensis,
viz. The Confect of
Alkermes,
and that of
Hyacinth.
The Confection of
Alkermes
Reformed.
TAKE the Juice of Kermes, sweet Apples, and Raspberries, of each strain'd lbij, Sugar of Roses lbij, mix and by a gentle Fire boil to the Consistence of Honey. The Aperitive Saffron, or Crocus Martis ℥iij, red Rose Buds reduc'd to a Powder, after having been first steep'd in Juice of Lemons ʒ vi,
Pearl, Coral, Crabs Eyes
and
burnt Hart's-Horn
laevigated with Oil of
Tartar
per
Deli
que
of each five Drams,
Citron Sanders
and
Bezoar,
or
Contrayerva Stone,
of each ʒ ss,
Musk
and
Ambergreese
may be added, at the Discretion of the Physician, but it is Judged much better to be left out. This Composition is preferable to that of the Shops, for the Intentions aim'd at, being more Cordial and Specifical to drive away Melancholy and the Malignity of the Bilous Juices, besides it is better appropriated to stop Fluxes, and to restore Strength.
The Confection of
Hyacinth
Reformed.
TAKE of the Seeds of Hyacinth and Viper's Bugloss, of each ℥ss, of the Roots of Tormentil, Bistort, Contrayerva, Scorzonera, Dictamny, of each ʒ iij, Citron and Orange-Peel dry'd of each ʒ iss, Betony and red Rose Flowers, of each ʒ i, Sorrel and Purslane Seed, of each ℈ij; burnt Hart's Horn, yellow Sanders, and white Amber, of each ʒ ij, Magistery of Pearl and Coral, and Crabs-Eyes prepar'd, of each ʒ vi Bole, Lemnian and Silesian Earths, of each ʒ ij, Saffron ℈iv, Camphore ℈i, Tincture of Kermes-Berries, extracted in Juice of Lemon, and reduc'd to the Consistence of Honey ℥ij; all these being rightly mix'd, and brought to a Powder, may be made into a Mass or Electuary, with Syrup of Lemons, Mulberries,
&c.
N. B.
In this Composition, instead of the Fragments of Precious Stones, or the Hyacinth, our Author has made Choice of the Seed which
Dioscorides,
thus describ'd,
Book
4.
Chap.
58. The Seed of the
Hyacinth,
says he, is Astringent, and Proper for the Compotision of Treacles, Myrrh is omitted, because of its ingrateful Taste, and as to the Perfumers of Musk and
Ambergreese,
they may be added at the Discretion of the Prescriber. But this Electuary seems better adapted, than that of the Shops, being more Cordial and Restorative, and may be us'd with good Effect in Malignant Disentery's and profuse Diarrhaea's, as also Pestilential Fevers, Small-Pox,
&c.
ANTIDOTARIA;
Or, a Collection of
Antidotes,
&c.
I Design'd to have given you Sir
Walter Rawleigh's
great Cordial from the original Manuscript, which you have taken into your
Dispensatory
from
Bates,
but the Variations are so great, and the Articles so Numerous, I refer 'em to a larger Work, and shall give you Sir
Walter Rawleigh's
grand
Diaphoretick,
taken from
Holten,
who liv'd with him, and also Sir
Kenelm Digby's
two sudorifick Waters, Vegetable and Mineral, appropriated to all burning Malignant Fevers and Pestilential Diseases.
Rawleigh's
DIAPHORETICK.
TAKE Mercury sublimate lbj. Crude Antimony, or rather the Regulus lbij, Grind them well on a Marble, till a Fume begin to arise, then put the Mixture into a Bolt-Head or Matrass, place this in a Cellar, and let it stand 15 or 20 Hours, till it runds into Butter, put that into a Glass Alembick, and distill till nothing will come over; encrease the Fire till a certain white Matter appears sublim'd on the Upper part, or Head of the Alembick; then cease till the Vessels are cold, and keep the white Sublimate a part, or separate, but the Residence remaining in the bottom is to be divided into two equal Parts, of which take one half, and all the Sublimate gain'd before, to this pour the Water which ascended in the first Distillation: Drive this till nothing further will Distil, and the Vessel being cool, the
Magma,
or
Caput Mortum,
with what is Sublimed must be Ground together in a Glass Mortar, and Water put in therewith to the Alembick: Drive this over again, and Repeat it 7 or 8 times, but give a large degree of Fire to the last, that the Sublimation may be exactly Regular: The Glasses being cold Collect your Sublimate, then Grind it again on a Marble, and in a small sublimating Furnace, sublime it Thirty or Forty times, Grinding it fine, every time, theoftener the better; the last time it must be reduc'd to an impalpable Powder, and put it into a Silver or Gold Vessel, to which pour the best Spirit of Wine, and burn it, reiterating this Work Seven or Eight times, at last you will have a perfect dry Powder, to be given from 6 to 12 Grains; this was a kind of
Panacea
to
Ralegh,
and given in Rheumatisms, Small-Pox, Plague, Malignant Fevers, and all cutaneous Diseases. It moves powerfully to Sweat.
Sir
Kenelm Digby's
Sudorifick
Cordial-Water.
Take of the Roots of Scorzonera, Gentian, Elicampane, Cinquefoil, Tormentil, Cyprus, Aristolochius of both Kinds, of each ℥iv. Zedoary ℥iij, the Husks of green Walnuts lbi, of the Leaves of the Orange and Lemon-Tree, Bay, Basil and Scordium, of each M. iv, the outward Rind of Lemons and Oranges, of each ℥x, Juniper-Berries ℥viij, Ivy-Berries ℥xij, clarified Juice of Valerian, Mead sweet, Scabious, Marygold, and Carduus, of each lbiij Rhenish Wine, and Rain Water, of each five Quarts, white Wine Vinegar lbv; bruise and mix all these together, and set 'em in Horse-Dung a Week, then Distill in Sand to the Consumption of half, and strain the Residue, making a strong Expression of the Magma, which Calcine, to white Ashes: The express'd Liquor is to be strain'd through a triple Filter, Distill'd again, till the Cordial Extract remains, which is to be kept by itself, the Salt of the
Magma
being added thereto, for the better preservation and encrease of its Virtue: Take of this Cordial now describ'd lbij. Salt of Tartar lbss, mix and rectifie together, and to the rectified Water, add Antimony Diaphoretick ℥ij, burnt Harts-Horn ℥iv; Mix and Digest in Sand eight Days, then Filter. The Dose is ℥i, to ʒ vi, by itself, or in Treacle-water in Malignant Fevers, you may add to this, Juice of Sorrel, or Lemons, and little a Sugar, with half a Dram of
Contrayerva.
The Mineral Sudorifick Water of Sir
Kenelm Digby.
TAKE of Crude Antimony, ground to a subtle Powder ℥i, Salt of Tartar ʒ vi, mix well, and put them together for some Days, in a moist Place, shake often, and at last they will dry; Repeat this two or three times, at last Grind this finely, put it into a Philosophical Egg, bury it in a Sand heat, or rather a Reverberatory, six or seven Days, at last give a Fire of the fourth degree of Heat, so that obscure Clouds may arise, the Matter will be of a red Colour, which take out, Grind afresh, and put it into a stronger Glass, pour on Spirit of Wine, and Extract, till the Spirit is tinged of a ruby Dye: Dose is from x to xx Drops in any convenient Liquor, as Wine, Treacle or Carduus-Water; it is a powerful and noble
Sudorifick.
Chalybeate Pills,
first invented in the
Plague
time, for strengthening the Stomach, opening Obstructions of the Spleen, and dissipating all the Melancholly and malignant Vapours. This Prescription seems to carry along with it the Perfection of the Art of Composition.
TAKE of the Species
Hiera Picra
℥ss, Aloes rosat. ʒ ij, ℈ij, mix, and of this take only ʒ iij, ℈i, of pure Vitriol of Iron ℈v, red Coral, Crab-Eyes, Mastick, Contrayerva Stone, Lapis Lazuli prepar'd finely, Salt of Worm-wood, of each ℈ij. ss, Balsam of
Peru,
as much as will make them into a Mass of
Pills
for ten Doses.
Every Dose of which will contain ʒ i, in these Proportions.
Of Hiera Piera, and Aloes ℈i, Vitriol of Iron ℈ss, Red, Coral and Crabs-Eyes.
Mastick, Contrayerva Lap. Lazuli, and Salt of Wormwood.
of each gr. v.
Another Composition of
Steel Pills,
to the same Effect.
TAKE of Mastick ʒ ij, Benjamin, natural Balsam, Gum Guajacum, red Coral, Pearl, Crabs-Eyes, burnt Harts-Horn, Ultramarine, Salt of Wormwood, of each ʒ i, Hiera Picra ℥ss, Aloes Rosat. ʒ ij, Salt of Steel, or Vitriol of Iron ʒ iss, with Balsam of
Peru,
make a Mass. The Dose is ʒ i, taken every Day.
A History of the several Compositions that make the
Contrayerva-Stone,
which is the Grand
Antidotarium.
THE
Contrayerva,
or
Drake Root,
is an
Indian
Plant, which some Judge to be of the Nature of
Tormentil.
This was first introduced into
France,
in 1602, and much prescrib'd by the Physicians at
Paris,
in the PIAGUE there at that Time, when it proved of excellent Service. The Root is tuberose and knotty, shooting forth many Hairs or Fibres of a yellowish, or rather brown Colour, which when chew'd gives an Aromatick flavour, and leaves an heat upon the Tongue, tho' no bitterness, or stipticity is observable. This grows in both the
Indies,
but most plentifully in the
West,
in the Kingdom of
Peru,
and that Part call'd
Ciarche
and
Tonsuglar.
The
Indians
Use it for Sallet; they much covet the Root, which they cut in Pieces, and put under the Soles of their Feet in Winter time: The
Goats
from eating of this Plant, are said to generate the
Bezoar Stone,
for the
Indians
observe those
Goats,
of which there are several Kinds, of which one is call'd
Bicuqua,
and those which do not feed upon this Plant, never generate any of these Stones; so that according to this Notion, their
Bezoar
seems to be a Concretion of Tartar, or the faeculent Part of the Aliment, form'd from the Digestion of the
Contrayerva Plant.
THE Stone in
India
is made from the Juice of the Root, and the whole Plant together, this is Reduced into Paste, and so form'd into Stones of various Sizes. The Root is given from a Dram to two, and hath had the Power to throw out Boils, Blains and Carbuncles, with great Success, in the
Plague
Time, which Encouraged the Physicians to invent several Compositions there from
The General Materials for the
Contrayerva Stone.
Contrayerva Root,
white Amber, Rock Chrystal, Snake-Root, Zedoary, Tormentil, Bistort, Angelica, red Coral, Camphore, Saffron, Crabs-Claws, Crabs-Eyes, burnt Harts-Horn, Vipers, Carline Thistle, Butter-Bur, Elecampane, Valerian, Pearl, Mastick, Cochineal, Isinglass, Lemnian, and Silesia Earth, Cerusse of Antimony-Flowers of ♀, Mosch and Amberbergreese to form it into a Mass, the Jelly of Vipers Skins, Isinglass, Harts-Horn, or an Extract of Scordium; or Scorzonera, with the white of an Egg may be necessary.
Various Forms of the
Contrayerva Stone,
each of which contain a Dose, which may be multiplied at Discretion.
TAKE Antimony Diaphoretick ℈i, Contrayerv. Bezoar Animal, Crabs-Claws, of each gr. x; make a Bole with Jelly of Harts-Horn, qs.
OR Take Diaphoretick Magisterial Contrayerv. and oriental Bezoar, of each gr. vi. Harts-Horn, Pearl, Coral and Crabs-Eyes prepar'd, of each gr. v. white Amber, Lemnian and Silesia Earth, of each gr. iv. Ambergreese gr. ij, make a Bole as before.
3dly, TAKE Ceruse of Antimony, Magistery of Coral, Pearl and Crabs-Eyes, of each ℈ss, Saffron and Contrayerva Root, of each gr. iv, make a Bole with Jelly of Harts-Horn, or Mucilage of Quince Seed.
4thly, TAKE Snake Root, Valerian and Contrayerva, of each ℈ss, Cochineal and Camphere, of each gr. iv. Bol-Arm. gr. vi, mix and make a fine Powder for one Dose, or a Bole, with Confect of Alkermes.
Bezoar Animal
prepared from
Harts-Horn.
TAKE the freshest and youngest Tips of Harts-Horn, Calcine to a perfect whiteness, Grind this to a Powder, and make it into Troches, with Syrup of Betony or Citron, first acuated with some Drops of Oil of Vitriol or Sulphur by the Bell.
The first Notion of the
Bezoardick Bole.
TAKE of the Contrayerva Stone ℥i. Oriental Bezoar ℥ss, Bezoar Animal ℥iv, Magistery of Coral, Pearl and Crabs-Eyes, of each ℥iiss, Crabs-Claws ℥iv, white Amber ℥ij, Lemnian and Silesia Earth ʒ vi, Rock Chrystal Calcined into an impalpable Powder ʒ x, Musk ʒ ss, with Jelly of Harts-Horn, made from a Tincture of Saffron; make this into a Paste, from whence Stones may be form'd. Take of the said Stone, gr. xx. Crollius Diaphoretick gr. x, for a Dose, and to raise the Alixipharmick power greater to the whole Composition of the Stone, add the Liver and Heart of Vipers ʒ ij; the Vipers Flesh and Bones dry'd according to Art ℥iv, to which put of the Roots of Angelica, Tormentil, Contrayerva, Zedoary, Scorzonera, Scordium, Rue and Orange-Water, of each ʒ i, made into a Mass, with Jelly of Vipers Skins.
Another COMPOSITION.
TAKE of Cerusse of Antimony or Flowers of the same, whether red or white ℥v, Harts-Horn prepar'd with Syrup of Angelica and Oil of Sulphur ℥ij, Roots of Tormentil, Scorzoner ℥ij, Butter-Bur, both the Valerians, Bunnian Seed, and Galangal, an ℥ss, Crabs-Claws, Crabs-Eyes, red Coral, Silesia-Earth, Cochineal, of each ℥i, Salt of Carduus, Mead sweet, Angelica, Tartar Vitriolated, sal Prunelle, of each ʒ ij, mix for a Paste, with Jelly of Harts-Horn, made up with Musk or Saffron, to this may be added, Vol. Salt of Vipers ℥i. Aur. Fulminans.
The Solar
Bezoardick Bole.
TAKE Crollius Diophoretick of ♁ gr. xij, Bezoar oriental gr. viij, Bezoar Animal, Magistery of Coral and Crabs-Eyes, an. gr. vij, Cochineal gr. vi, Aurum Fulminans gr. iv, Ambergreese gr. ij, mix for a Dose.
N. B.
If the foregoing Magisteries are made with Spirit of Vitriol, Oil of Sulphur, &c. the Medicine will be the more Effectual, and better resist the Putrefaction of the Malignity.
The Northern
Bezoartick-Stone.
TAKE
Hartman's
Diaphoretick Antimony, Magistery of Gold, red Coral an. ʒ vi, common Antimony Diaphoretick, Harts-Horn Calcined, Crabs-Eyes prepar'd an ℥i, Crabs-Claws in Powder ʒ ij, Ambergreese ʒ i, Musk ℈i, make this into Paste with Jelly of Isinglass, in Rose-Water.
The Southern
Bezoartick-Stone.
TAKE of the Magisterial Diaphoretick ℥i, Cerusse of ♁ ℥iij, burnt Harts-Horn, Crabs-Eyes, of Vipers Flesh, Cochineal an. ℥iss, Magistery of Pearl, and Coral an. ʒ vi, Silesian-Earth ℥i, yellow Sanders, Orange-Peel an. ℥ss, Roots of Valerian, Butter-Bur, Scorzonera, Contrayerva, Seeds of Angelica an. ʒ vi, Ambergreese, Musk an ʒ ss, make a Powder, and then a Paste with Jelly of Hart's-Horn, the Dose from a ℈i, ℈ij,
In the Year
1628,
the following Prescriptions of the
Contrayerva-Stone
were directed.
TAKE Contrayerva Root, ℥ij, Hart's-Horn prepar'd and Lemnian-Earth, of each ℥i, Cochineal ℥ss, Margarit ℥iv, Snake-Roct ℥ss, with Isinglass and Juice of Kermes, make a Mass; whereof take ʒ ss, in any Cordial-Water.
OR, TAKE Contrayerva, Snake-Root, of each ℥i, Pearl and Crabs-Eyes an. ℥ss, Saffron ʒ ij, Cochineal ʒ ij, mix and give ℈ss, to ℈i, in any appropriated Vehicle.
In the Year
1636,
when the
PLAGUE
Raged in
London,
these Forms were Prescrib'd.
TAKE Crabs-Claws in Powder, Bezoar Animal, Syrup of Betony, Kermes and Citron an. ℥iv, Contrayerva, and Snake-Root an. ℥v, Seed of Angelica an. ℥i, Antimony, Diaphoretick ℥vi, Ambergreese ʒ ij, mix. The Dose is ℈i, to ʒ ss. Take Contrayerva, and Snake-Root, with Crabs-Claws powder'd an ʒ ij, Pearl, and Coral an. ʒ iij, Crollius, Diaphoretick of Antimony ʒ i. The Dose ℈i.
The
TREACLE-STONE.
TAKE the whole Viper reduc'd to Powder ℥i, Crabs-Eyes ℥iv,
Hartman's
Diaphoretick, or Flowers of ♁, fix'd by the Fire ℥ij, Mother of Pearl, Cochineal, and white Amber an. ℥iss, Roots of Tormentil, Bistort, Scorzonera an. ℥ij, Kermes Berry, Orange-Peel and Angelica an. ℥ss, Saffron with Venice-Treacle, qs. make a Mass. Dose ℈ to ʒ i.
A Composition very Successful in the
Small-Pox, Measles, Milliary-Fever,
&c.
TAKE
Hartman's
Diaphoretick gr. x, Contrayerva-Stone, and Bezoar an. gr. viij, Hart's-Horn prepar'd with Oil of Vitriol, Coral, Crabs-Eyes, of each gr. vi, Silesian, Lemnian Earth, and Cochineal an gr. v, mix for a Dose in Treacle-Water.
The white
Contrayerva-Stone.
TAKE of the Contrayerva-Root ℥i, Hart's-Horn, and Crabs-Claws, laevigated on a Marble, with Carduus-Water an. ℥i, Magistery of Pearl and Coral an. ℥ss; make this up with Jelly of Hart's-Horn and Isinglass; the Dose ʒ ss, to Children ℈i.
The red
Contrayerva-Stone.
TAKE of the Contrayerva-Root ℥iss, Antimony Diaphoretick, Crabs-Eyes an. ʒ x, Chochineal ℥iss, Bezoar Mineral ℥ss, Grind these together, and they will be of an excellent red Colour; the Dose from ℈i, to ʒ ss, in the Confluent
Small-Pox
and
Purple-Fevers.
Confect of
Vipers,
or the Grand
Antidote
against all Sorts of
Poyson.
TAKE Vipers in the
Spring,
Cut their Heads off, and cleanse them well in white Wine; dry them, and reduce them with their Hearts and Livers to Powder, of this so prepared, take ℥iv, Roots of Contrayerva ℥ij, Tormentil, Scorzonera an. ℥iss, Roots of Avens, Vervain, Carline, Bastard, Saffron, Fraxinel, Cinquefoil, Elecampane, the outward Rind of the Lemon and Orange an. ℥i; Roots of Swallow wort, both the the Valerians, Burdock, Butter-Bur, Gentitian, Zedoary an. ʒ vi, Angelica-Roots ʒ ss, Leaves of Scordium, Rue, Malabathrum, Paul's Betony, Sanicle, Winter-green an ʒ vi, Flowers of Self-heal,
Spanish Broom,
Betony, Mary-gold, Mead sweet Oranges an. ʒ v, Seeds of Rue, Scabious, Burdock, Vipers Bugloss, Vervain, Sorrel, Purslane, Carduus,
St.
John's-Wort, Mary-golds, Broom an. ʒ iij, Citron Sanders, Rhodium, Sassafrass, Costus, Schaenath, Calamus Aromaticus, Harts-Horn and the Rasping of Human Sculls, Lemnian Earth, Gum Guajacum, Myrrh, Mastick, Sandarac, Olibanum an. ℥ss, white Amber, Pearl and Coral prepared;
Hartman's
Diaphoretick of Antimony ʒ ij, Mace, Cloves, Cinnamon, Infused in Juice of Lemon an. ʒ vi, all these well power'd separately, may be afterwards mix'd together in the following
Electuary.
Take of fresh Juniper-Berries lbiv, the Parings of Apples and Quinces an. lbss, Roots of Sorrel and Succory an. ℥iv, Scabious, Mary-gold, Wood-Sorrel, Borage, the whole Plants an. M. ij, Flowers of Sage, Rosemary, red Roses, Germander, Broom and Mugwort an. Pug. iij, Kermes Berries, Citron Seeds an. ʒ ij, Orange-Peel and Rhodium Rasped an. ʒ iss; Boil all in
Spanish
Wine and Carduus-Water, of each equal Parts, to which add Juice of Strawberries, Raspberries, Cherries or Quinces lbij, strain this and Boil the Express'd Liquor to the Consistence of Honey: Of which take two Parts to one of the Spices, or Powder before Prescrib'd, adding thereto upon Occasion, to every Dose of Antimony Diaphoretick ℈i, Aurum Fulminans ℈ss, Oil of Sulphur gr. iv; Dose ʒ ss, to ℈iv.
The Imperial Cordial Water
in
Pestilential-Fevers.
TAKE of the dry'd Roots of Swallowwort, Angelica, Masterwort, Gentian, Elecampane ℥ij, Roots of Carline Thistle, Burdock, Birthworth, Bistort, Tormentil, Galingal, Scorzonera, Contrayerva an. ℥iij, Leaves of Hyssop, Majoram, Rue, Bay, Mint, Balm, Mead sweet, Wormwood an. lbiij, Flowers of Centaury, Broom, St. Johns-wort, Mary-gold, Sage, Lavender and Orange an. ℥i, Cinnamon, Cloves, Mace, Nutmegs, Zedoary, Galangal, Calamus an. ʒ x, Juniper-Berries, Rhodium and Citron Sanders an. ℥iij, Orange-Peel ℥vi, Strong-Wine, or Brandy lbxij, Infuse for 8 or 10 Days, then Distill, afterwards sweeten with Loaf-Sugar, to which add a few Drops of Oil of Cinnamon, Burgamot, or Essence of Ambergreese.
The
Golden Elixir
of
LIFE.
THE
Aurm Potabile
of
Blanc
was made of the best Spirit of Wine, Circulated with Honey, Musk and Ambergreese, according to the Description of
Gabel Rhoverus,
in the second Part of his
Antidotarium,
pag. 383. This is one of the most potent Liquors, yet still more Penetrating, and Efficacious, according to the following Composition; of this
Aurum Potabile,
Extracted without Fire lbvi,
Aurum Fulminans,
precipiated by Oil of Tartar, which is better, the Chrystals of Gold, as taught hereafter to prepare ℥ij, Choice Pearl ℥iv, Sugar-Candy lbiv, Ambergreese ℥ij, Musk ℥ss. Saffron ℥iv, Spirit of Salt, doubly-Extracted lbi, Spirit of Wine dephlegmated lbiv, pour this upon the Ambergreese, Musk and Saffron to Extract a Tincture by a gentle Heat; then dissolve the Sugar in Spirit of Honey; the Gold and Pearl will come to an Easie Dissolution in Spirit of Salt; so that in eight Days time you will have each of them distinctly prepared in order for a Mixture, which you are to make in a double Cucurbit, well luted in the Junctures, and buried in a Sand Furnace, for forty Days, during which time a regular Circulation is to be perform'd, at last Decant from thence a clear limpid Liquor, which keep in Glass Viols close stop't. The Dose is from two Drops to a Dram; this is the most powerful Corroborative in the
Plague,
in Hysterick Suffocations, Faintings, Vertigo's and Flatulent Disorders of the Stomach and Bowels.
CHRYSTALS of Gold are made thus. Take of Leaf Gold, what you please, pour thereon a double or triple Part of pure Spirit of Salt rectified, make a Dissolution, and Cohobate six or eight times in an Alembick, with an Hole quite through the Head of it, at last force the matter over by a strong Fire, and the Chrystals will ascend to the Neck of the Vessel, these Chrystals are dissolvable in almost any Liquor, and to be separated again by Spirit of Salt, and reduc'd to their pristine Form.
THUS Gentlemen, I have given you a a short Specimen of my design'd Reformation of your
London Dispensatory,
and Hope as it will be Useful to the Publick, so it will meet with a Candid Reception, and hearty Approbation from your learned Society, which is the utmost Ambition, of Gentlemen, with all
Die 4is xiij, Ap. 1721.
Duty and Respect, Your most Humble, most Devoted and most Obedient Servant,
J. BROWNE.
FINIS.